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However, the stopcodon is preceded by a run of 11 consecutive adenosines.
2
The single-base pair mutation causes a frameshift, which results in premature stopcodon.
3
This duplication results in a frame shift and premature stopcodon.
4
A premature stopcodon UGA appeared to be most responsive to PTC124 treatment.
5
The 5'UTR contains two false AUG initiation codons followed by a stopcodon.
1
The remainder of the sequence corresponded to the 3'-region of the mRNA downstream from the terminationcodon.
2
Furthermore, the most C-terminally located premature terminationcodon mutation fails to rescue the progenitor cell proliferation defect in hippocampal slice cultures from Bcl11b-deficient mice.
3
RNA analysis revealed that an alternative splice site within exon 1 was used leading to a premature terminationcodon within exon 2.
4
Affected animals carry a mutation that predicts a premature terminationcodon in exon 8 and a peptide that is 5% the size of normal dystrophin.
5
Due to premature terminationcodons, none encodes functional protein.